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Ecdysis Uneven Skin Duo

35,000.00

Ecdysis Uneven Skin Duo harnesses the dual action of the Ecdysis Uneven Skin Concentrate and Ecdysis Uneven Skin Emulsion to target all forms of hyperpigmentation at various points in the melanin pathway.

Active Ingredients: 5% Tranexamic acid, 4% Kojic dipalmatate, 4% Niacinamide, 2% Alpha Arbutin, 2% Kojic Acid, 2% N-Acetyl Glucosamine.

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SKU: Variable Product -2 Category: Tags: ,

Description

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Full Ingredients List

Ecdysis Uneven Skin Concentrate: Aqua (Water), Aloe Barbadensis Leaf Juice, Dimethyl Isosorbide, Tranexamic Acid, Propanediol, Glycerin, Niacinamide, Alpha-Arbutin, N-acetyl Glucosamine, Camellia Sinensis Leaf Extract, Centella Asiatica Extract, Carbomer, Ethylhexylglycerin (and) Phenoxyethanol (Euxyl®️ 9010). ———————————————————— Ecdysis Uneven Skin Emulsion: Aqua (Water), Caprylic/Capric Triglyceride, C12–C15 Alkane, Dimethyl Isosorbide, Glycerin, Kojic Dipalmitate, Propylene Glycol, Cetearyl Olivate (and) Sorbitan Olivate (Olivem 1000), Kojic Acid, Cetearyl Alcohol, Glyceryl Stearate, Bisabolol, Tocopherol, Sodium Metabisulfite, Hydroxyethylcellulose, Ethylhexylglycerin (and) Phenoxyethanol (Euxyl®️ 9010)

How to Use

Skincare Application Process

Skincare Application Process

Cleanser (A gentle soap-free facial wash)

Hydrating Toner (Optional)

Uneven Skin Concentrate

Uneven Skin Emulsion - A pea size

Moisturize

Important Notice

Application Period: Nighttime .

Dermatologist Guide

Derm-Recommended Protocol

Derm-Recommended Protocol

A well rounded approach to target hyperpigmentation and achieve brighter, more even skin

Step Product Frequency Key Benefit
1 Core Treatment
Ecdysis Uneven Skin Duo
3-4+ nights/week
adjust based on tolerance
Reduces melanin production at cellular level
2 Exfoliation Boost
• Ecdysis Mandelic Acid 10% + phytomedical blend serum (normal/dry/sensitive skin types )
• Ecdysis Salicylic Acid 2% + phytomedical blend serum (oily/acne-prone skin type)
1-3 nights/week
Never same night as the uneven skin duo unless tolerated
Gently sweeps away dull, pigment-loaded skin cells and helps your other skincare products work even better.
3 Essential Protection
SPF 50+
Every morning, last step in your morning skincare routine
Protects skin against harmful UV rays and sun damage, preventing new dark spots while supporting a brighter, more even complexion.
4 Hydration Product
Ecdysis Acetyl Hexapeptide-8 + Panthenol Cream
Morning and night
Keeps skin barrier intact preventing sensitivity & inflammation that can trigger extra melanin production
Weekly Tip: Take one night off from actives to focus on hydration and skin recovery.

Product Specifications

pH Level 4.5–5.5 (Optimally balanced to match skin's natural pH)
Size 40ml each
Shelf Life / PAO 12 months after opening
Storage Cool dry place, away from direct sunlight
Texture Lightweight, fast-absorbing

Scientific Validation

Ecdysis Scientific Validation

Ecdysis Uneven Skin Duo

Scientific Validation of Ingredients

Clinically Proven Ingredients

1

Tranexamic Acid, Niacinamide, and N-Acetyl Glucosamine (NAG)

A prospective 12-week study (n=38, diverse skin types) showed that a serum containing tranexamic acid, niacinamide, and N-acetyl glucosamine significantly reduced global and lesional post-inflammatory hyperpigmentation (PIH) starting at week 4, with continued improvement to week 12. In vitro, TXA inhibited melanogenesis, supporting its cellular mechanism of action. No tolerability issues were reported.

Reference: Draelos et al., 2023, abstract 50536
2

Niacinamide + NAG Combination

In a large, controlled clinical trial, the pairing of 4% niacinamide + 2% NAG consistently reduced the appearance of hyperpigmentation.

Reference: Kimball et al., 2010
3

Kojic Acid

A 2022 review highlights kojic acid as a well-studied tyrosinase inhibitor used for freckles, age spots, post inflammatory hyperpigmentation, and melasma. Clinical data supports its efficacy at ≤2% concentration, though it is limited by stability and irritation risks.

Reference: Phasha et al., 2022
4

Kojic Acid Dipalmitate (KDP)

A 2023 review on KDP shows that this ester derivative of kojic acid has improved stability, permeability, and lower toxicity compared to kojic acid and demonstrates potential for more stable long-term skin lightening.

Reference: Ayuhastuti et al., 2023
5

Alpha-Arbutin

A 2021 review confirms that α-arbutin safely inhibits tyrosinase activity and melanosome maturation, making it a popular and effective skin lightening agent. It is positioned as a safer alternative to hydroquinone, widely used in cosmetic and dermatologic applications for all forms of hyperpigmentation.

Reference: Chandorkar et al., 2021

References

  • Chandorkar, N., Tambe, S., Amin, P., & Madankar, C. S. (2021). Alpha Arbutin as a skin lightening agent: A review. International Journal of Pharmaceutical Research, 13(2).
  • Draelos, Z. D., Edison, B., Trehan, S., Li, W. H., Singh, S., Feng, L., Batchvarova, N., Parsa, R., & Guerrero, R. (2023). A tranexamic acid, niacinamide, and acetyl glucosamine facial serum clinically improved PIH and post-acne marks in a diverse population. Journal of the American Academy of Dermatology, 88(5), AB114. [Abstract 50536].
  • Kimball, A. B., Kaczvinsky, J. R., Li, J., Robinson, L. R., Matts, P. J., Berge, C. A., Miyamoto, K., & Bissett, D. L. (2010). Reduction in the appearance of facial hyperpigmentation after use of moisturizers with a combination of topical niacinamide and N-acetyl glucosamine: Results of a clinical study. British Journal of Dermatology, 162(2), 435–441.
  • Phasha, V., Senabe, J., Ndzotoyi, P., Okole, B., Fouche, G., & Chuturgoon, A. (2022). Review on the use of kojic acid—A skin-lightening ingredient. Cosmetics, 9(3), 64.
  • Ayuhastuti, A., Syah, I. S. K., Megantara, S., & Chaerunisaa, A. Y. (2023). A comprehensive review of the cosmetic application of kojic acid dipalmitate: Kojic acid derivative with improved properties. Preprints, 2023.